UNDERSTANDING ALS

What is Amyotrophic Lateral Sclerosis?

Also known as Lou Gehrig's Disease

ALS is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord. It breaks the connection between the brain and muscles — and together, we're fighting to change that.

ALS Families: Contact us, and share your story! Supporters: How You Can Help!

30,000+

Americans currently living with ALS

5,000+

New cases diagnosed each year in the U.S.

2–5 Years

Average life expectancy after diagnosis

90%

Of cases occur without family history (sporadic ALS)

How ALS Affects the Body

When motor neurons — the messengers between your brain and muscles — begin to die, the body gradually loses the ability to move, speak, eat, and eventually breathe.

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Motor Neurons

ALS attacks the nerve cells responsible for controlling voluntary muscle movement, disrupting signals from brain to body.

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Signal Disruption

As neurons degenerate, the electrical signals that tell muscles to move become weaker and eventually stop entirely.

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Muscle Weakness

Without nerve stimulation, muscles weaken and atrophy. Early signs include difficulty gripping, tripping, or dropping things.

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Progressive Spread

ALS typically starts in one area — a hand, foot, or tongue — and gradually spreads to other muscle groups throughout the body.

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Speech & Swallowing

Many people with ALS experience slurred speech and difficulty swallowing as the muscles of the mouth and throat weaken.

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Breathing Difficulty

As respiratory muscles weaken, breathing support becomes necessary. This is the most critical challenge for those living with ALS.

Our Shifstrong Family: Voices in the Fight Against ALS

Behind every diagnosis is a story, a fight, and a community. At Shifstrong, we believe in the power of shared experiences. Hear from those affected by ALS. We value every perspective, whether you are a patient, caregiver, a family member, or a friend, your story natters! You all offer unique insights into this battle, and your vulnerability will help the next generation of ALS patients and their families navigate this journey. Thank you for all you do for our community, together we will fight ALS.